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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRB10 All Species: 20.91
Human Site: S481 Identified Species: 51.11
UniProt: Q13322 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13322 NP_001001549.1 594 67231 S481 S Q S P L H P S T L S T V I H
Chimpanzee Pan troglodytes XP_001154916 594 67198 S481 S Q S P L H P S T L S T V I H
Rhesus Macaque Macaca mulatta XP_001083447 775 86284 S662 S Q S P L H P S T L S T V I H
Dog Lupus familis XP_849638 440 48261 L350 W M T A C R L L K G L E G K L
Cat Felis silvestris
Mouse Mus musculus Q60760 621 70566 T509 Q S P L H P S T L N A V I H R
Rat Rattus norvegicus P0CE43 599 67864 S486 S Q S P L H P S T L N S V I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506127 625 71314 S512 S Q S P L H P S T L S T V I H
Chicken Gallus gallus
Frog Xenopus laevis Q6DCV1 653 72662 P486 P E T K S A T P T V T K R P P
Zebra Danio Brachydanio rerio Q6PFT9 646 70983 M483 P P P P P D P M F P P P P P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34400 779 87484 S647 N Q S P A S F S V N S C Q Q S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 74.7 59.2 N.A. 67.3 68.6 N.A. 83.5 N.A. 22.3 22.7 N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: 100 100 75.8 64.3 N.A. 74 75.4 N.A. 88.8 N.A. 37.9 38.3 N.A. N.A. N.A. 35.5 N.A.
P-Site Identity: 100 100 100 0 N.A. 0 86.6 N.A. 100 N.A. 6.6 13.3 N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 20 100 N.A. 100 N.A. 33.3 13.3 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 0 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 10 50 0 0 0 0 0 0 0 10 50 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 50 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 0 0 10 0 10 0 % K
% Leu: 0 0 0 10 50 0 10 10 10 50 10 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 20 10 0 0 0 0 % N
% Pro: 20 10 20 70 10 10 60 10 0 10 10 10 10 20 10 % P
% Gln: 10 60 0 0 0 0 0 0 0 0 0 0 10 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % R
% Ser: 50 10 60 0 10 10 10 60 0 0 50 10 0 0 10 % S
% Thr: 0 0 20 0 0 0 10 10 60 0 10 40 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 10 0 10 50 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _